Concepedia

Suppression of SHP-2 and ERK Signalling Promotes Self-Renewal of Mouse Embryonic Stem Cells

Tom Burdon, Craig Stracey, Ian Chambers, Jennifer Nichols, Austin Smith

Developmental Biology · 1999 · 571 citations · 67 references

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67

Establishment in culture of pluripotential cells from mouse embryos

Martin Evans, M. H. Kaufman · Nature · 1981 · 8.6K citations

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Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells.

Gail R. Martin · Proceedings of the National Academy of Sciences · 1981 · 5.7K citations

, , +16

A synthetic inhibitor of the mitogen-activated protein kinase cascade.

David T. Dudley, Long Pang, Stuart J. Decker et al. · Proceedings of the National Academy of Sciences · 1995 · 2.7K citations · Full text

, , +15

A general method of<i>in vitro</i>preparation and specific mutagenesis of DNA fragments: study of protein and DNA interactions

Russell Higuchi, Barbara Krummel, Randall K. Saiki · Nucleic Acids Research · 1988 · 2.4K citations · Full text

, , +12

Blastocyst implantation depends on maternal expression of leukaemia inhibitory factor

Colin L. Stewart, Petr Kašpar, Lisa J. Brunet et al. · Nature · 1992 · 2K citations

, , +16