Concepedia

N-Hydroxy-1,2-disubstituted-1H-benzimidazol-5-yl acrylamides as novel histone deacetylase inhibitors: Design, synthesis, SAR studies, and in vivo antitumor activity

Haishan Wang, Niefang Yu, Hongyan Song, Dizhong Chen, Yong Zou, Weiping Deng, Pek Ling Lye, Joyce Wei Wei Chang, Melvin Ng, Stéphanie Blanchard,

Bioorganic & Medicinal Chemistry Letters · 2009 · 29 citations · 15 references

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15

Protein secondary structure prediction based on position-specific scoring matrices 1 1Edited by G. Von Heijne

David T. Jones · Journal of Molecular Biology · 1999 · 5.5K citations

, , +10

Multiple sequence alignment with the Clustal series of programs

Nucleic Acids Research · 2003 · 4.9K citations · Full text

, , +14

Evaluation and Reparametrization of the OPLS-AA Force Field for Proteins via Comparison with Accurate Quantum Chemical Calculations on Peptides

George A. Kaminski, Richard A. Friesner, Julian Tirado‐Rives et al. · The Journal of Physical Chemistry B · 2001 · 4.1K citations

, , +17

Semianalytical treatment of solvation for molecular mechanics and dynamics

W. Clark Still, Anna Tempczyk, Ronald C. Hawley et al. · Journal of the American Chemical Society · 1990 · 3.7K citations

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Structures of a histone deacetylase homologue bound to the TSA and SAHA inhibitors

Michael S. Finnin, Jill R. Donigian, Alona Cohen et al. · Nature · 1999 · 1.7K citations

, , +12