Concepedia

Pek Ling Lye

PL

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Publications

2

Citations

120

H-Index

2

Active since

2009

Affiliations

Singapore Science Park(Current)

Pek Ling Lye is an author at Singapore Science Park specializing in medicinal chemistry, drug discovery, and benzimidazole chemistry.

Publications per year

2009–2011

2

Publications

2

Discovery of (2<i>E</i>)-3-{2-Butyl-1-[2-(diethylamino)ethyl]-1<i>H</i>-benzimidazol-5-yl}-<i>N</i>-hydroxyacrylamide (SB939), an Orally Active Histone Deacetylase Inhibitor with a Superior Preclinical Profile

Haishan Wang, Niefang Yu, Dizhong Chen et al. · Journal of Medicinal Chemistry · 2011 · 91 citations · Full text

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N-Hydroxy-1,2-disubstituted-1H-benzimidazol-5-yl acrylamides as novel histone deacetylase inhibitors: Design, synthesis, SAR studies, and in vivo antitumor activity

Haishan Wang, Niefang Yu, Hongyan Song et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 29 citations · Full text

, , +11

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