Concepedia

Pharmacokinetics of Amitriptyline and One of Its Metabolites, Nortriptyline, in Rats: Little Contribution of Considerable Hepatic First-Pass Effect to Low Bioavailability of Amitriptyline Due to Great Intestinal First-Pass Effect

Soo Kyung Bae, Kyung Yang, Dipendra K. Aryal, Yoon G. Kim, Myung G. Lee

Journal of Pharmaceutical Sciences · 2008 · 22 citations · 17 references

DOI

Concepts

References

17

Critical evaluation of the potential error in pharmacokinetic studies of using the linear trapezoidal rule method for the calculation of the area under the plasma level-time curve

Win L. Chiou · Journal of Pharmacokinetics and Biopharmaceutics · 1978 · 623 citations

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COMPARISON OF IN VITRO DRUG METABOLISM BY LUNG, LIVER, AND KIDNEY OF SEVERAL COMMON LABORATORY SPECIES

Charles L. Litterst, Edward G. Mimnaugh, Reginald L. Reagan et al. · Drug Metabolism and Disposition · 1975 · 270 citations

, , +15

Pharmacokinetics and pharmacodynamics of furosemide in protein-calorie malnutrition

So H. Kim, Young Choi, Myung G. Lee · Journal of Pharmacokinetics and Biopharmaceutics · 1993 · 218 citations

, , +12

Evaluation of potential causes for the incomplete bioavailability of furosemide: Gastric first-pass metabolism

Myung G. Lee, Win L. Chiou · Journal of Pharmacokinetics and Biopharmaceutics · 1983 · 174 citations

, , +14

Dose-Independent Pharmacokinetics of Metformin in Rats: Hepatic and Gastrointestinal First-Pass Effects

Young Hee Choi, Sang G. Kim, Myung G. Lee · Journal of Pharmaceutical Sciences · 2006 · 124 citations

, , +14