Concepedia

Hepatic Bioavailability

Hepatic Bioavailability is the fraction of an administered drug dose that reaches the systemic circulation unchanged following hepatic first-pass metabolism, distinguishing it from intestinal or other pre-systemic metabolic processes.

564

Publications

30.4K

Citations

2.6K

Authors

715

Institutions

Publications per year

2017–2026

76

Parents

Children

Publications

564

Influence of Piperine on the Pharmacokinetics of Curcumin in Animals and Human Volunteers

Guido Shoba, David C. Joy, Thangam Joseph et al. · Planta Medica · 1998 · 1.9K citations

, , +13

HIGH ABSORPTION BUT VERY LOW BIOAVAILABILITY OF ORAL RESVERATROL IN HUMANS

Thomas Walle, Faye Hsieh, Mark H. DeLegge et al. · Drug Metabolism and Disposition · 2004 · 1.8K citations

, , +15

A Study on the Fate of Curcumin in the Rat

Bo Wahlström, G. Blennow · Acta Pharmacologica et Toxicologica · 1978 · 623 citations

, , +17

Drug and Bile Acid Transporters in Rosuvastatin Hepatic Uptake: Function, Expression, and Pharmacogenetics

Richard Ho, Rommel G. Tirona, Brenda F. Leake et al. · Gastroenterology · 2006 · 610 citations · Full text

, , +14

Phase I Randomized, Double-Blind Pilot Study of Micronized Resveratrol (SRT501) in Patients with Hepatic Metastases—Safety, Pharmacokinetics, and Pharmacodynamics

Lynne Howells, D.P. Berry, P.J. Elliott et al. · Cancer Prevention Research · 2011 · 432 citations · Full text

, , +16

1–5 of 564

Authors

2.6K

  1. MH
    Mitsuru Hashida

    Kyoto University, Japan

    12 publications · 692 citations

    12

    h-index

  2. MN
    Makiya Nishikawa

    Kyoto University, Japan

    11 publications · 611 citations

    11

    h-index

  3. YT
    Yoshinobu Takakura

    Kyoto University, Japan

    8 publications · 504 citations

    8

    h-index

  4. TT
    Tung‐Hu Tsai

    National Yang Ming Chiao Tung University, Taiwan

    6 publications · 523 citations

    6

    h-index

  5. FY
    Fumiyoshi Yamashita

    Kyoto University, Japan

    6 publications · 261 citations

    6

    h-index

1–5 of 2.6K

Institutions

715

  1. Kyoto University

    Kyoto, Japan

    15 h-index

    75 publications

    3.3K citations

  2. Kyoto Pharmaceutical University

    Kyoto, Japan

    14 h-index

    54 publications

    2.3K citations

  3. The University of Queensland

    Brisbane, Australia

    10 h-index

    26 publications

    942 citations

  4. Pfizer (United States)

    New York, United States

    10 h-index

    51 publications

    2.7K citations

  5. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    8 h-index

    31 publications

    1.8K citations

  6. Bristol-Myers Squibb (United States)

    New York, United States

    8 h-index

    60 publications

    2K citations

  7. Seoul National University

    Seoul, South Korea

    7 h-index

    19 publications

    601 citations

  8. Princess Alexandra Hospital

    Brisbane, Australia

    7 h-index

    12 publications

    355 citations

1–8 of 715

Venues

  1. Drug Metabolism and Disposition

    39 publications · 4.5K citations

    26

    h-index

  2. Clinical Pharmacology & Therapeutics

    CPT · 23 publications · 1.5K citations

    18

    h-index

  3. PubMed

    Repository · 25 publications · 808 citations

    16

    h-index

  4. Xenobiotica

    19 publications · 640 citations

    15

    h-index

  5. 15

    h-index

1–5