Concepedia

Disulfide-stabilized diabody antiCD19/antiCD3 exceeds its parental antibody in tumor-targeting activity

Wei Li, Ming Yang, Yan Yan, Shuangjing Li, Min Wang, Wang Jianxiang

Cellular Oncology · 2012 · 10 citations · 21 references

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References

21

"Diabodies": small bivalent and bispecific antibody fragments.

Philipp Holliger, Teresa Di Prospero, Greg Winter · Proceedings of the National Academy of Sciences · 1993 · 875 citations · Full text

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A recombinant bispecific single-chain antibody, CD19 × CD3, induces rapid and high lymphoma-directed cytotoxicity by unstimulated T lymphocytes

Anja Löffler, Peter Kufer, Ralf Lutterbüse et al. · Blood · 2000 · 445 citations

, , +17

Optimization of antibody binding to FcγRIIa enhances macrophage phagocytosis of tumor cells

John O. Richards, Sher Karki, Greg A. Lazar et al. · Molecular Cancer Therapeutics · 2008 · 304 citations

, , +17

Strictly Target Cell-dependent Activation of T Cells by Bispecific Single-chain Antibody Constructs of the BiTE Class

Klaus Brischwein, Larissa Parr, Stefan Pflanz et al. · Journal of Immunotherapy · 2007 · 189 citations

, , +17

High Level Secretion of a Humanized Bispecific Diabody from Escherichia coli

Zhenping Zhu, Gerardo Zapata, Refaat Shalaby et al. · Nature Biotechnology · 1996 · 123 citations

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