Philipp Holliger

"Diabodies": small bivalent and bispecific antibody fragments.

Philipp Holliger, Teresa Di Prospero, Greg Winter · Proceedings of the National Academy of Sciences · 1993 · 870 citations · Full text

Dimeric Antibody Fragments, Peptide Engineering, Immunology +16

Synthetic Genetic Polymers Capable of Heredity and Evolution

Vitor B. Pinheiro, Alexander I. Taylor, Christopher Cozens et al. · Science · 2012 · 697 citations · Full text

Engineering, Genetic Information Storage, Genetics +17

Ribozyme-Catalyzed Transcription of an Active Ribozyme

Aniela Wochner, James Attwater, Alan Coulson et al. · Science · 2011 · 399 citations

Directed evolution of polymerase function by compartmentalized self-replication

Farid J. Ghadessy, Jennifer L. Ong, Philipp Holliger · Proceedings of the National Academy of Sciences · 2001 · 386 citations · Full text

In-ice evolution of RNA polymerase ribozyme activity

James Attwater, Aniela Wochner, Philipp Holliger · Nature Chemistry · 2013 · 281 citations · Full text

Natural Sciences, In-ice Evolution, Rna Structure Prediction +3