Concepedia

Different forms of cell death induced by putative BCL2 inhibitors

Meike Vogler, Kathrin Weber, David Dinsdale, Ingo Schmitz, Klaus Schulze‐Osthoff, Martin J.S. Dyer, Gerald M. Cohen

Cell Death and Differentiation · 2009 · 202 citations · 36 references

DOIFull text

Open access

Concepts

References

36

Proapoptotic BAX and BAK: A Requisite Gateway to Mitochondrial Dysfunction and Death

Michael C. Wei, Wei‐Xing Zong, Emily H. Cheng et al. · Science · 2001 · 3.9K citations · Full text

, , +17

An inhibitor of Bcl-2 family proteins induces regression of solid tumours

Tilman Oltersdorf, Steven W. Elmore, Alexander R. Shoemaker et al. · Nature · 2005 · 3.4K citations

, , +14

The Pathophysiology of Mitochondrial Cell Death

Douglas R. Green, Guido Kroemer · Science · 2004 · 3.4K citations

, , +17

Intracellular Adenosine Triphosphate (ATP) Concentration: A Switch in the Decision Between Apoptosis and Necrosis

Marcel Leist, Barbara Single, Anna Federica Castoldi et al. · The Journal of Experimental Medicine · 1997 · 1.9K citations · Full text

, , +14

The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak/Bax if Mcl-1 is neutralized

Mark F. van Delft, Andrew H. Wei, Kylie D. Mason et al. · Cancer Cell · 2006 · 1.2K citations · Full text

, , +10