Inhibitory effects of celastrol on rat liver cytochrome P450 1A2, 2C11, 2D6, 2E1 and 3A2 activity

The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions.

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Protein measurement using bicinchoninic acid: elimination of interfering substances

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Celastrol Suppresses Angiogenesis-Mediated Tumor Growth through Inhibition of AKT/Mammalian Target of Rapamycin Pathway

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Chemoprevention Strategy, Cancer Biology, Rapamycin Pathway +16

Cytochrome P450-dependent drug oxidation activities in liver microsomes of various animal species including rats, guinea pigs, dogs, monkeys, and humans

Tsutomu Shimada, Mayumi Mimura, Kiyoshi Inoue et al. · Archives of Toxicology · 1997 · 173 citations

Biochemistry, Guinea Pigs, Various Animal Species +14

Neuroprotective effects of compounds with antioxidant and anti-inflammatory properties in a Drosophila model of Parkinson's disease

Katharina Faust, Stephan Gehrke, Yufeng Yang et al. · BMC Neuroscience · 2009 · 151 citations · Full text