J�rgen Lehmann

The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions.

J�rgen Lehmann, David D. McKee, M. A. Watson et al. · Journal of Clinical Investigation · 1998 · 1.6K citations · Full text

Medicine, Molecular Biology, Pharmacology +14

MUC18, a marker of tumor progression in human melanoma, shows sequence similarity to the neural cell adhesion molecules of the immunoglobulin superfamily.

J�rgen Lehmann, G. Riethmüller, Jennifer Johnson · Proceedings of the National Academy of Sciences · 1989 · 469 citations · Full text

Medicine, Molecular Biology, Oncology +16

A novel N-aryl tyrosine activator of peroxisome proliferator-activated receptor-gamma reverses the diabetic phenotype of the Zucker diabetic fatty rat.

Kathleen K. Brown, Brad R. Henke, Steven G. Blanchard et al. · Diabetes · 1999 · 168 citations

Medicine, Endocrinology, Pharmacology +17

COUP orphan receptors are negative regulators of retinoic acid response pathways.

P Tran, X K Zhang, Gilles Salbert et al. · Molecular and Cellular Biology · 1992 · 142 citations · Full text

Life Sciences, Molecular Biology, Molecular Genetics +17

Serum-free growth medium for the cultivation of a wide spectrum of mammalian cells in stirred bioreactors

Volker J�ger, J�rgen Lehmann, Peter Friedl · Cytotechnology · 1988 · 97 citations

Engineering, Bioengineering, Biotechnology +17