Assessing the In Vivo Epidermal Barrier in Mice: Dye Penetration Assays

Common loss-of-function variants of the epidermal barrier protein filaggrin are a major predisposing factor for atopic dermatitis

Alan D. Irvine, Ana Terron-Kwiatkowski, Yiwei Zhao et al. · Nature Genetics · 2006 · 3K citations

Medicine, Dermatology, Genetics +16

Claudin-based tight junctions are crucial for the mammalian epidermal barrier

Mikio Furuse, Masaki Hata, Kyoko Furuse et al. · The Journal of Cell Biology · 2002 · 1.5K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +13

Loss-of-function mutations in the gene encoding filaggrin cause ichthyosis vulgaris

Frances J.D. Smith, Alan D. Irvine, Ana Terron-Kwiatkowski et al. · Nature Genetics · 2006 · 1K citations

Life Sciences, Genetics, Molecular Genetics +9

External antigen uptake by Langerhans cells with reorganization of epidermal tight junction barriers

Akiharu Kubo, Keisuke Nagao, Mariko Yokouchi et al. · The Journal of Experimental Medicine · 2009 · 475 citations · Full text

Life Sciences, Cell Biology, Immunology +17

E‐cadherin is essential for in vivo epidermal barrier function by regulating tight junctions

Judith A Tunggal, Iris Helfrich, Annika Schmitz et al. · The EMBO Journal · 2005 · 475 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +13