Pharmacokinetic Scale-up: Accurate Prediction of Human Pharmacokinetic Profiles from Animal Data

Interspecies scaling, allometry, physiological time, and the ground plan of pharmacokinetics

Harold Boxenbaum · Journal of Pharmacokinetics and Biopharmaceutics · 1982 · 646 citations

Pharmacy, Pharmacokinetics, Physiology +11

Quantitative Relations in the Physiological Constitutions of Mammals

E. F. Adolph · Science · 1949 · 504 citations

Life Sciences, Biology, Physiology +6

Animal scale-up

Robert L. Dedrick · Journal of Pharmacokinetics and Biopharmaceutics · 1973 · 394 citations

Prediction of the disposition ofβ-lactam antibiotics in humans from pharmacokinetic parameters in animals

Yasufumi Sawada, Manabu Hanano, Yuichi Sugiyama et al. · Journal of Pharmacokinetics and Biopharmaceutics · 1984 · 117 citations

Pharmacy, Pharmacokinetics, Pharmacology +13

Comparative pharmacokinetics of benzodiazepines in dog and man

Harold Boxenbaum · Journal of Pharmacokinetics and Biopharmaceutics · 1982 · 78 citations

Medicine, Pharmacokinetics, Pharmacology +8