Comparative pharmacokinetics of benzodiazepines in dog and man

A physiological approach to hepatic drug clearance

G. Wilkinson, David G. Shand · Clinical Pharmacology & Therapeutics · 1975 · 1.9K citations

Pharmacy, Pharmacokinetics, Pharmacology +17

Hepatic clearance of drugs. I. Theoretical considerations of a “well-stirred” model and a “parallel tube” model. Influence of hepatic blood flow, plasma and blood cell binding, and the hepatocellular enzymatic activity on hepatic drug clearance

K. Sandy Pang, Malcolm Rowland · Journal of Pharmacokinetics and Biopharmaceutics · 1977 · 798 citations

Pharmacy, Pharmacokinetics, Pharmacology +17

Statistical estimations in pharmacokinetics

Harold Boxenbaum, Sidney Riegelman, Robert M. Elashoff · Journal of Pharmacokinetics and Biopharmaceutics · 1974 · 728 citations

Pharmacy, Clinical Pharmacokinetics, Pharmacokinetics +6

Interspecies scaling, allometry, physiological time, and the ground plan of pharmacokinetics

Harold Boxenbaum · Journal of Pharmacokinetics and Biopharmaceutics · 1982 · 646 citations

Pharmacy, Pharmacokinetics, Physiology +11

Animal scale-up

Robert L. Dedrick · Journal of Pharmacokinetics and Biopharmaceutics · 1973 · 394 citations