The HIV-1 matrix protein p17 can be efficiently delivered by intranasal route in mice using the TLR 2/6 agonist MALP-2 as mucosal adjuvant

A nuclear localization signal within HIV-1 matrix protein that governs infection of non-dividing cells

Michael Bukrinsky, Sheryl Haggerty, Michael P. Dempsey et al. · Nature · 1993 · 801 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +16

Proline‐rich (PxxP) motifs in HIV‐1 Nef bind to SH3 domains of a subset of Src kinases and are required for the enhanced growth of Nef+ viruses but not for down‐regulation of CD4.

Kalle Saksela, Genhong Cheng, David Baltimore · The EMBO Journal · 1995 · 555 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15

Isolation, Structure Elucidation, and Synthesis of a Macrophage Stimulatory Lipopeptide from <i>Mycoplasma fermentans</i> Acting at Picomolar Concentration

Peter F. Mühlradt, Michael Kieß, Holger Meyer et al. · The Journal of Experimental Medicine · 1997 · 400 citations · Full text

Life Sciences, Immunology, Microbiology +13

HIV-1 infection of nondividing cells: C-terminal tyrosine phosphorylation of the viral matrix protein is a key regulator

Philippe Gallay, Simon Swingler, Christopher Aiken et al. · Cell · 1995 · 305 citations · Full text

Life Sciences, Infectious Diseases, Molecular Biology +17

HIV-1 nef leads to inhibition or activation of T cells depending on its intracellular localization

Andreas S. Baur, Earl T. Sawai, Paul Dazin et al. · Immunity · 1994 · 302 citations

Life Sciences, Immunology, Infectious Diseases +15