Concepedia

Destruction of Claspin by SCFβTrCP Restrains Chk1 Activation and Facilitates Recovery from Genotoxic Stress

Niels Mailand, Simon Bekker‐Jensen, Jiří Bártek

Molecular Cell · 2006 · 253 citations · 35 references

DOI

Concepts

References

35

SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27

Andrea C. Carrano, Esther Eytan, Avram Hershko et al. · Nature Cell Biology · 1999 · 1.5K citations

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Mitotic and G <sub>2</sub> Checkpoint Control: Regulation of 14-3-3 Protein Binding by Phosphorylation of Cdc25C on Serine-216

Cheng‐Yuan Peng, Paul R. Graves, Richard S. Thoma et al. · Science · 1997 · 1.3K citations

, , +17

ATR-Mediated Checkpoint Pathways Regulate Phosphorylation and Activation of Human Chk1

Hui Zhao, Helen Piwnica‐Worms · Molecular and Cellular Biology · 2001 · 1.1K citations · Full text

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The ATM–Chk2–Cdc25A checkpoint pathway guards against radioresistant DNA synthesis

Jacob Falck, Niels Mailand, Randi G. Syljuåsen et al. · Nature · 2001 · 1.1K citations

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ATM- and cell cycle-dependent regulation of ATR in response to DNA double-strand breaks

Ali Jazayeri, Jacob Falck, Claudia Lukas et al. · Nature Cell Biology · 2005 · 1K citations

, , +14