Interferon regulatory factor 9 is a key mediator of hepatic ischemia/reperfusion injury

hSIR2SIRT1 Functions as an NAD-Dependent p53 Deacetylase

Homayoun Vaziri, Scott Dessain, Elinor Ng Eaton et al. · Cell · 2001 · 2.6K citations · Full text

Transcriptional Regulation, Hsir2sirt1 Functions, Molecular Biology +4

Negative Control of p53 by Sir2α Promotes Cell Survival under Stress

Jianyuan Luo, Anatoly Nikolaev, Shin‐ichiro Imai et al. · Cell · 2001 · 2.1K citations · Full text

Cell Regulation, Cell Signaling, Apoptosis +9

The nuclear factor HMGB1 mediates hepatic injury after murine liver ischemia-reperfusion

Allan Tsung, Rohit Sahai, Hiroyuki Tanaka et al. · The Journal of Experimental Medicine · 2005 · 1.1K citations · Full text

Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice

Hwei-Ling Cheng, Raúl Mostoslavsky, Shinichi Saito et al. · Proceedings of the National Academy of Sciences · 2003 · 1.1K citations · Full text

Sirt1 Function, Genetics, Apoptosis +19

Acetylation of the p53 DNA-Binding Domain Regulates Apoptosis Induction

Stephen M. Sykes, Hestia Mellert, Marc A. Holbert et al. · Molecular Cell · 2006 · 731 citations · Full text

Apoptosis, Cell Death, Tumor Suppressor +2