Hestia Mellert

Methylated lysine 79 of histone H3 targets 53BP1 to DNA double-strand breaks

Yentram Huyen, Omar Zgheib, Richard A. DiTullio et al. · Nature · 2004 · 871 citations

Life Sciences, Biochemistry, Molecular Biology +13

Acetylation of the p53 DNA-Binding Domain Regulates Apoptosis Induction

Stephen M. Sykes, Hestia Mellert, Marc A. Holbert et al. · Molecular Cell · 2006 · 740 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +10

Global analysis of p53-regulated transcription identifies its direct targets and unexpected regulatory mechanisms

Mary A. Allen, Zdeněk Andrysík, Veronica L. Dengler et al. · eLife · 2014 · 254 citations · Full text

Life Sciences, Cancer Biology, Molecular Biology +14

Nuclear Cyclin D1/CDK4 Kinase Regulates CUL4 Expression and Triggers Neoplastic Growth via Activation of the PRMT5 Methyltransferase

Priya Aggarwal, Laura Pontano Vaites, J. Kim et al. · Cancer Cell · 2010 · 249 citations · Full text

Medicine, Cancer Biology, Molecular Biology +14

Aligning tumor mutational burden (TMB) quantification across diagnostic platforms: phase II of the Friends of Cancer Research TMB Harmonization Project

Diana Merino Vega, Laura M. Yee, Lisa M. McShane et al. · Annals of Oncology · 2021 · 182 citations · Full text

Medicine, Bioinformatics, Oncology +17