Concepedia

Tumour predisposition in mice heterozygous for a targeted mutation in Nf1

Tyler Jacks, T. Shane Shih, Earlene M. Schmitt, Roderick T. Bronson, André Bernards, Robert A. Weinberg

Nature Genetics · 1994 · 777 citations · 54 references

DOI

Concepts

References

54

Mutation and Cancer: Statistical Study of Retinoblastoma

Alfred G. Knudson · Proceedings of the National Academy of Sciences · 1971 · 7.6K citations · Full text

, , +16

Current protocols in molecular biology

Trends in Biochemical Sciences · 1988 · 4.3K citations

, , +10

Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells

Kirk R. Thomas, Mario R. Capecchi · Cell · 1987 · 2.4K citations

, , +12

Effects of an Rb mutation in the mouse

Tyler Jacks, Amin Fazeli, Earlene M. Schmitt et al. · Nature · 1992 · 1.8K citations

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Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes

Suzanne L. Mansour, Kirk R. Thomas, Mario R. Capecchi · Nature · 1988 · 1.7K citations

, , +15