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2-(1H-Imidazol-4-yl)ethanamine and 2-(1H-pyrazol-1-yl)ethanamine side chain variants of the IGF-1R inhibitor BMS-536924

Mark G. Saulnier, David B. Frennesson, Mark D. Wittman, Kurt Zimmermann, Upender Velaparthi, David R. Langley, Charles Struzynski, Xiaopeng Sang, Joan M. Carboni, Aixin Li,

Bioorganic & Medicinal Chemistry Letters · 2008 · 26 citations · 25 references

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25

Inhibition of the insulin-like growth factor receptor-1 tyrosine kinase activity as a therapeutic strategy for multiple myeloma, other hematologic malignancies, and solid tumors

Constantine S. Mitsiades, Nicholas Mitsiades, Ciaran J. McMullan et al. · Cancer Cell · 2004 · 611 citations

, , +17

Copper−Diamine-Catalyzed <i>N</i>-Arylation of Pyrroles, Pyrazoles, Indazoles, Imidazoles, and Triazoles

Jon C. Antilla, Jeremy M. Baskin, Timothy E. Barder et al. · The Journal of Organic Chemistry · 2004 · 576 citations

, , +17

In vivo antitumor activity of NVP-AEW541—A novel, potent, and selective inhibitor of the IGF-IR kinase

Carlos Garcı́a-Echeverrı́a, Mark Pearson, Andreas Marti et al. · Cancer Cell · 2004 · 538 citations · Full text

, , +9

Targeting Tyrosine Kinases in Cancer: The Second Wave

José Baselga · Science · 2006 · 477 citations

, , +15

Cyclolignans as Inhibitors of the Insulin-Like Growth Factor-1 Receptor and Malignant Cell Growth

Ada Girnita, Leonard Girnita, Fabrizio Del Prete et al. · Cancer Research · 2004 · 359 citations

, , +16