Concepedia

PH domain leucine-rich repeat protein phosphatase 1 contributes to maintain the activation of the PI3K/Akt pro-survival pathway in Huntington's disease striatum

Ana Saavedra, Juan Manuel García‐Martínez, Xavier Xifró, Albert Giralt, Jesús F. Torres-Peraza, Josep M. Canals, Miguel Díaz‐Hernández, José J. Lucas, Jordi Alberch, Esther Pérez‐Navarro

Cell Death and Differentiation · 2009 · 61 citations · 39 references

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39

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes

Marcy E. MacDonald · Cell · 1993 · 8.3K citations · Full text

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Exon 1 of the HD Gene with an Expanded CAG Repeat Is Sufficient to Cause a Progressive Neurological Phenotype in Transgenic Mice

Laura Mangiarini, Kirupa Sathasivam, Mary J. Seller et al. · Cell · 1996 · 3.1K citations · Full text

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A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. The Huntington's Disease Collaborative Research Group.

Manish A. Shah, Nicole A. Datson, Lakshmi Srinidhi et al. · Cell · 1993 · 3.1K citations

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Mechanism of activation of protein kinase B by insulin and IGF-1.

Dario R. Alessi, Mirjana Andjelković, B. Caudwell et al. · The EMBO Journal · 1996 · 3K citations · Full text

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Mice lacking brain-derived neurotrophic factor develop with sensory deficits

Patrik Ernfors, Kuo‐Fen Lee, Rudolf Jaenisch · Nature · 1994 · 1.1K citations

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