Juan Manuel García‐Martínez

mTOR complex 2 (mTORC2) controls hydrophobic motif phosphorylation and activation of serum- and glucocorticoid-induced protein kinase 1 (SGK1)

Juan Manuel García‐Martínez, Dario R. Alessi · Biochemical Journal · 2008 · 881 citations · Full text

Molecular Regulation, Mtorc1 Activity, Cellular Physiology +20

Ku-0063794 is a specific inhibitor of the mammalian target of rapamycin (mTOR)

Juan Manuel García‐Martínez, Jennifer L. Moran, Rosemary G. Clarke et al. · Biochemical Journal · 2009 · 460 citations · Full text

New Insights into mTOR Signaling: mTORC2 and Beyond

Dario R. Alessi, Laura R. Pearce, Juan Manuel García‐Martínez · Science Signaling · 2009 · 186 citations

Molecular Physiology, Signal Transduction, Cell Regulation +13

Mutation of the PDK1 PH Domain Inhibits Protein Kinase B/Akt, Leading to Small Size and Insulin Resistance

José R. Bayascas, Stephan Wullschleger, Kei Sakamoto et al. · Molecular and Cellular Biology · 2008 · 127 citations · Full text

Ribosomal S6 Kinase, Molecular Biology, Insulin Signaling +19

PH domain leucine-rich repeat protein phosphatase 1 contributes to maintain the activation of the PI3K/Akt pro-survival pathway in Huntington's disease striatum

Ana Saavedra, Juan Manuel García‐Martínez, Xavier Xifró et al. · Cell Death and Differentiation · 2009 · 61 citations · Full text

Neurodegenerative Diseases, Molecular Neuroscience, Molecular Physiology +12