Brain-Derived Neurotrophic Factor Regulates the Onset and Severity of Motor Dysfunction Associated with Enkephalinergic Neuronal Degeneration in Huntington's Disease

Josep M. Canals, José Ramón Pineda, Jesús F. Torres-Peraza, +6

Journal of Neuroscience

Striatal DopamineAmyotrophic Lateral SclerosisMedicineGeneticsNeurological Function +13

Suppressing aberrant GluN3A expression rescues synaptic and behavioral impairments in Huntington's disease models

Sònia Marco, Albert Giralt, Miloš Petrović, +15

Nature Medicine

Disease ModelsNeurodegenerative DiseasesSynaptic PlasticityMolecular NeuroscienceGenetics +8

Full Motor Recovery Despite Striatal Neuron Loss and Formation of Irreversible Amyloid-Like Inclusions in a Conditional Mouse Model of Huntington's Disease

Miguel Díaz‐Hernández, Jesús F. Torres-Peraza, Alejandro Salvatori-Abarca, +4

Journal of Neuroscience

Mitochondrial DysfunctionGeneticsFull Motor RecoveryHuntingtin-containing InclusionsDisease Gene Identification +20

PH domain leucine-rich repeat protein phosphatase 1 contributes to maintain the activation of the PI3K/Akt pro-survival pathway in Huntington's disease striatum

Ana Saavedra, Juan Manuel García‐Martínez, Xavier Xifró, +7

Cell Death and Differentiation

Neurodegenerative DiseasesMolecular NeuroscienceMolecular PhysiologyLeucine-rich Repeat ProteinDisease Striatum +10

Protective neuronal induction of ATF5 in endoplasmic reticulum stress induced by status epilepticus

Jesús F. Torres-Peraza, Tobías Engel, Raquel Martín‐Ibáñez, +6

Brain

Cell DeathEndoplasmic Reticulum StressTranscription Factor 5Synaptic SignalingSocial Sciences +21

Effect of glatiramer acetate (Copaxone®) on the immunophenotypic and cytokine profile and BDNF production in multiple sclerosis: A longitudinal study

Yolanda Blanco, Esther Moral, Meritxell Costa, +8

Neuroscience Letters

InflammationNeurobiology Of DiseaseAutoimmune DiseaseSystemic DiseasesBdnf Production +11

Transgenic mice overexpressing the full-length neurotrophin receptor TrkC exhibit increased catecholaminergic neuron density in specific brain areas and increased anxiety-like behavior and panic reaction

Mara Dierssen, Mónica Gratacòs, Ignasi Sahún, +15

Neurobiology of Disease

Panic ReactionPsychiatryBehavioral NeuroscienceMedicineSpecific Brain Areas +9

Disruption of striatal glutamatergic transmission induced by mutant huntingtin involves remodeling of both postsynaptic density and NMDA receptor signaling

Jesús F. Torres-Peraza, Albert Giralt, Juan Manuel García‐Martínez, +3

Neurobiology of Disease

Synaptic PlasticityStriatal Glutamatergic TransmissionSynaptic TransmissionNeurotransmitterMolecular Biology +8

Overexpression of synphilin-1 promotes clearance of soluble and misfolded alpha-synuclein without restoring the motor phenotype in aged A30P transgenic mice

Nicolas Casadei, Anne-Maria Pöhler, Cristina Tomás‐Zapico, +12

Human Molecular Genetics

Knockout MouseNeurodegenerative DiseasesSynphilin-1 Promotes ClearanceProtein ClearanceMotor Phenotype +12

Age-dependent decline of motor neocortex but not hippocampal performance in heterozygous BDNF mice correlates with a decrease of cortical PSD-95 but an increase of hippocampal TrkB levels

Olga Carretón, Albert Giralt, Jesús F. Torres-Peraza, +5

Experimental Neurology

Motor NeocortexNeurophysiologyNeuroanatomyAge-dependent DeclineCortical Remodeling +7