Metabolic effects of tumour necrosis factor alpha in NMRI mice

Shock and Tissue Injury Induced by Recombinant Human Cachectin

Kevin J. Tracey, Bruce Beutler, Stephen F. Lowry et al. · Science · 1986 · 2.6K citations

Lung Inflammation, Immunology, Cell Death +18

Anti-cachectin/TNF monoclonal antibodies prevent septic shock during lethal bacteraemia

Kevin J. Tracey, Yuman Fong, David Hesse et al. · Nature · 1987 · 2.5K citations

Humoral Response, Immunology, Sepsis +5

Identity of tumour necrosis factor and the macrophage-secreted factor cachectin

Bruce Beutler, David A. Greenwald, J D Hulmes et al. · Nature · 1985 · 1.1K citations

Inflammation, Cytokine, Tumour Necrosis Factor +13

Purification of cachectin, a lipoprotein lipase-suppressing hormone secreted by endotoxin-induced RAW 264.7 cells.

Bruce Beutler, James A. Mahoney, Nguyen Le Trang et al. · The Journal of Experimental Medicine · 1985 · 825 citations · Full text

Immunology, Cellular Physiology, Inflammation +18

Cachectin/tumor necrosis factor induces cachexia, anemia, and inflammation.

Kevin J. Tracey, Kirk R. Manogue, Yuman Fong et al. · The Journal of Experimental Medicine · 1988 · 739 citations · Full text

Immunology, Food Intake, Cell Death +18