Methylglyoxal induces endoplasmic reticulum stress and DNA demethylation in the Keap1 promoter of human lens epithelial cells and age-related cataracts

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Michael D. Abràmoff, Paulo Magalhães, Sunanda J. Ram · Utrecht University Repository (Utrecht University) · 2004 · 11.9K citations · Full text

Engineering, Image Files, Digital Pathology +20

Cellular differentiation, cytidine analogs and DNA methylation

Peter A. Jones, Shirley M. Taylor · Cell · 1980 · 1.8K citations

Chromatin, Epigenetic Change, Genetics +5

The antioxidant responsive element. Activation by oxidative stress and identification of the DNA consensus sequence required for functional activity

Thomas H. Rushmore, Marcia R. Morton, C.B. Pickett · Journal of Biological Chemistry · 1991 · 1.5K citations · Full text

Reductive Stress, Biosynthesis, Dna +15

BAX and BAK Regulation of Endoplasmic Reticulum Ca ²⁺ : A Control Point for Apoptosis

Luca Scorrano, Scott A. Oakes, Joseph T. Opferman et al. · Science · 2003 · 1.4K citations

Mitochondrial Dysfunction, Apoptosis, Cell Death +19

Hydroxylation of 5-Methylcytosine by TET1 Promotes Active DNA Demethylation in the Adult Brain

Junjie U. Guo, Yijing Su, Chun Zhong et al. · Cell · 2011 · 1.3K citations · Full text

Chromatin, Chromatin Remodeling, Epigenetic Change +10