Jefferson Chan

Transcription Factor Nrf1 Mediates the Proteasome Recovery Pathway after Proteasome Inhibition in Mammalian Cells

Senthil K. Radhakrishnan, Candy S. Lee, Patrick Young et al. · Molecular Cell · 2010 · 524 citations · Full text

Reductive Stress, Proteasome Inhibition, Protein Function +12

Nrf2-Deficient Mice Have an Increased Susceptibility to Dextran Sulfate Sodium–Induced Colitis

Tin Oo Khor, Mou‐Tuan Huang, Ki Han Kwon et al. · Cancer Research · 2006 · 518 citations

Deficiency of the Nrf1 and Nrf2 Transcription Factors Results in Early Embryonic Lethality and Severe Oxidative Stress

Laura Leung, Mandy Kwong, Stephen Hou et al. · Journal of Biological Chemistry · 2003 · 306 citations · Full text

Increased Susceptibility of Nrf2 Knockout Mice to Colitis-Associated Colorectal Cancer

Tin Oo Khor, Mou‐Tuan Huang, Auemduan Prawan et al. · Cancer Prevention Research · 2008 · 302 citations · Full text

Inflammation, Nrf 2, Immunology +9

Liver-specific inactivation of the Nrf1 gene in adult mouse leads to nonalcoholic steatohepatitis and hepatic neoplasia

Zhenrong Xu, Linyun Chen, Laura Leung et al. · Proceedings of the National Academy of Sciences · 2005 · 298 citations · Full text

Lipid Peroxidation, Pathology, Cell Death +25