Laura Leung

Heterodimeric JAK–STAT activation as a mechanism of persistence to JAK2 inhibitor therapy

Priya Koppikar, Neha Bhagwat, Outi Kilpivaara et al. · Nature · 2012 · 359 citations · Full text

Deficiency of the Nrf1 and Nrf2 Transcription Factors Results in Early Embryonic Lethality and Severe Oxidative Stress

Laura Leung, Mandy Kwong, Stephen Hou et al. · Journal of Biological Chemistry · 2003 · 306 citations · Full text

Liver-specific inactivation of the Nrf1 gene in adult mouse leads to nonalcoholic steatohepatitis and hepatic neoplasia

Zhenrong Xu, Linyun Chen, Laura Leung et al. · Proceedings of the National Academy of Sciences · 2005 · 298 citations · Full text

Lipid Peroxidation, Pathology, Cell Death +25

Deficiency in the Nuclear Factor E2-related Factor-2 Transcription Factor Results in Impaired Adipogenesis and Protects against Diet-induced Obesity

Jingbo Pi, Laura Leung, Peng Xue et al. · Journal of Biological Chemistry · 2010 · 289 citations · Full text

Nutrition, Metabolic Disorder, Genetics +19

Nrf1 Is Critical for Redox Balance and Survival of Liver Cells during Development

Lingyun Chen, Mandy Kwong, Ronghua Lu et al. · Molecular and Cellular Biology · 2003 · 146 citations · Full text