Concepedia

Joseph T. Opferman

JT

65

Publications

10.5K

Citations

43

H-Index

1993

Active since

Affiliations

St. Jude Children's Research Hospital(Current)

Dana-Farber Cancer Institute

Harvard University

University of Tennessee Health Science Center

University of Chicago

Joseph T. Opferman is an author at St. Jude Children's Research Hospital specializing in medicine, cell biology, and cell death.

Top concepts

MedicineCell BiologyCell DeathCell SignalingImmunologyTumor BiologyNatural SciencesApoptosisBiochemistrySignal Transduction

Publications per year

1993–2024

65

Publications

65

BAX and BAK Regulation of Endoplasmic Reticulum Ca <sup>2+</sup> : A Control Point for Apoptosis

Luca Scorrano, Scott A. Oakes, Joseph T. Opferman et al. · Science · 2003 · 1.4K citations

Mitochondrial Dysfunction, Apoptosis, Cell Death +19

NIX is required for programmed mitochondrial clearance during reticulocyte maturation

Rachel L. Schweers, Ji Zhang, Mindy S. Randall et al. · Proceedings of the National Academy of Sciences · 2007 · 892 citations · Full text

Development and maintenance of B and T lymphocytes requires antiapoptotic MCL-1

Joseph T. Opferman, Anthony Letai, Caroline Beard et al. · Nature · 2003 · 778 citations

Autoimmune Disease, Lymphocyte Development, Immunology +9

Obligate Role of Anti-Apoptotic MCL-1 in the Survival of Hematopoietic Stem Cells

Joseph T. Opferman, Hiromi Iwasaki, Christy C. Ong et al. · Science · 2005 · 562 citations

Mcl-1 Gene, Mixed-phenotype Acute Leukemia, Apoptosis +19

Gene expression-based chemical genomics identifies rapamycin as a modulator of MCL1 and glucocorticoid resistance

Guo Wei, David Twomey, Justin Lamb et al. · Cancer Cell · 2006 · 512 citations · Full text

Natural Sciences, Molecular Biology, Resistance Mutation (Virology) +8

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