Concepedia

Histone H4 lysine 16 acetylation regulates cellular lifespan

Weiwei Dang, Kristan K. Steffen, Rocco Perry, Jean Dorsey, F. Brad Johnson, Ali Shilatifard, Matt Kaeberlein, Brian K. Kennedy, Shelley L. Berger

Nature · 2009 · 674 citations · 27 references

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27

The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms

Matt Kaeberlein, Mitch McVey, Leonard Guarente · Genes & Development · 1999 · 2.3K citations · Full text

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Genomic Instability and Aging-like Phenotype in the Absence of Mammalian SIRT6

Raúl Mostoslavsky, Katrin F. Chua, David B. Lombard et al. · Cell · 2006 · 1.6K citations · Full text

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Extrachromosomal rDNA Circles— A Cause of Aging in Yeast

David Sinclair, Leonard Guarente · Cell · 1997 · 1.5K citations · Full text

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SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin

Eriko Michishita, Ronald A. McCord, Elisabeth Berber et al. · Nature · 2008 · 1.1K citations

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Cellular Senescence in Aging Primates

Utz Herbig, Mark Ferreira, Laura Condel et al. · Science · 2006 · 1.1K citations

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