Cyclopropane-based conformational restriction of GABA by a stereochemical diversity-oriented strategy: Identification of an efficient lead for potent inhibitors of GABA transports

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Pharmacy, Medicinal Chemistry, Pharmacology +17

Is There a Difference between Leads and Drugs? A Historical Perspective

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Life Sciences, Neurobiology, Neuroscience +13

Tiagabine, SK&F 89976-A, CI-966, and NNC-711 are selective for the cloned GABA transporter GAT-1

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Medicine, Pharmacotherapy, Pharmacogenetics +8

New aspects of catalytic asymmetric cyclopropanation

Michael P. Doyle, Marina Protopopova · Tetrahedron · 1998 · 313 citations

Natural Sciences, Chemical Engineering, Chemistry +14