Concepedia

MDM2 promotes the proteasomal degradation of p73 through the interaction with Itch in HeLa cells

Natsumi Kubo, Rintaro Okoshi, Kumiko Nakashima, Osamu Shimozato, Akira Nakagawara, Toshinori Ozaki

Biochemical and Biophysical Research Communications · 2010 · 23 citations · 25 references

DOI

Concepts

References

25

Mdm2 promotes the rapid degradation of p53

Ygal Haupt, Ruth Maya, Anat Kazaz et al. · Nature · 1997 · 4.5K citations

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Regulation of p53 stability by Mdm2

Michael H.G. Kubbutat, Stephen N. Jones, Karen H. Vousden · Nature · 1997 · 3.3K citations

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The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53

Martin Scheffner, Jon M. Huibregtse, Richard D. Vierstra et al. · Cell · 1993 · 2.4K citations

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Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53

Reiko Honda, Hirofumi Tanaka, Hideyo Yasuda · FEBS Letters · 1997 · 1.9K citations

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Monoallelically Expressed Gene Related to p53 at 1p36, a Region Frequently Deleted in Neuroblastoma and Other Human Cancers

Mourad Kaghad, H Bonnet, Annie Yang et al. · Cell · 1997 · 1.6K citations · Full text

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