Concepedia

Pyrrolidinobenzoic acid inhibitors of influenza virus neuraminidase: modifications of essential pyrrolidinone ring substituents

Wayne J. Brouillette, Saroj N. Bajpai, Shoukath M. Ali, Sadanandan E. Velu, Venkatram R. Atigadda, Barbara Lommer, James B. Finley, Ming Luo, Gillian M. Air

Bioorganic & Medicinal Chemistry · 2003 · 28 citations · 23 references

DOI

Concepts

References

23

Rational design of potent sialidase-based inhibitors of influenza virus replication

Mark von Itzstein, Wen‐Yang Wu, Gaik B. Kok et al. · Nature · 1993 · 1.9K citations

, , +16

Influenza Neuraminidase Inhibitors Possessing a Novel Hydrophobic Interaction in the Enzyme Active Site:  Design, Synthesis, and Structural Analysis of Carbocyclic Sialic Acid Analogues with Potent Anti-Influenza Activity

Choung U. Kim, Willard Lew, Matthew A. Williams et al. · Journal of the American Chemical Society · 1997 · 1.1K citations

, , +17

Characterization of temperature sensitive influenza virus mutants defective in neuraminidase

Peter Palese, Kiyotake Tobita, Masahiro Ueda et al. · Virology · 1974 · 796 citations

, , +11

Influenzavirus neuraminidase and neuraminidase-inhibition test procedures.

M Aymard-Henry, M. T. Coleman, W. R. Dowdle et al. · PubMed · 1973 · 421 citations

, , +7

BCX-1812 (RWJ-270201):  Discovery of a Novel, Highly Potent, Orally Active, and Selective Influenza Neuraminidase Inhibitor through Structure-Based Drug Design

Y.S. Babu, Pooran Chand, Shanta Bantia et al. · Journal of Medicinal Chemistry · 2000 · 378 citations · Full text

, , +6