Glucuronidation of the Antiretroviral Drug Efavirenz by UGT2B7 and an in Vitro Investigation of Drug-Drug Interaction with Zidovudine

Antiretroviral Treatment of Adult HIV Infection

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Pharmacy, Pharmacology, Pharmacotherapy +17

Antiretroviral Treatment of Adult HIV Infection

Scott M. Hammer, Joseph J. Eron, Peter Reiss et al. · JAMA · 2008 · 1K citations

Pharmacy, Pharmacology, Pharmacotherapy +17

Efavirenz plasma levels can predict treatment failure and central nervous system side effects in HIV-1-infected patients

Catia Marzolini, Amalio Telenti, Laurent A. Décosterd et al. · AIDS · 2001 · 836 citations

Pharmacy, Pharmacokinetics, Pharmacology +16

The Cytochrome P450 2B6 (CYP2B6) Is the Main Catalyst of Efavirenz Primary and Secondary Metabolism: Implication for HIV/AIDS Therapy and Utility of Efavirenz as a Substrate Marker of CYP2B6 Catalytic Activity

Bryan A. Ward, J. Christopher Gorski, David R. Jones et al. · Journal of Pharmacology and Experimental Therapeutics · 2003 · 594 citations

Medicine, Pharmacokinetics, Pharmacology +17

The glucuronidation of opioids, other xenobiotics, and androgens by human UGT2B7Y(268) and UGT2B7H(268).

Birgit L. Coffman, Christopher D. King, Gladys R. Rios et al. · PubMed · 1998 · 326 citations

Medicine, Biochemistry, Pharmacology +13