Platelet Membrane Glycoprotein IIb/IIIa: Member of a Family of Arg-Gly-Asp—Specific Adhesion Receptors

Robert Pytela, Michael D. Pierschbacher, Mark H. Ginsberg, +2

Science

Cell AdhesionGlycobiologyMolecular BiologyCytoskeletonCellular Physiology +22

Design of potent and specific integrin antagonists. Peptide antagonists with high specificity for glycoprotein IIb-IIIa.

Robert M. Scarborough, M.A. Naughton, Wei-Ning Teng, +6

Journal of Biological Chemistry

Non-peptide fibrinogen receptor antagonists. 1. Discovery and design of exosite inhibitors

George D. Hartman, Melissa S. Egbertson, Wasyl Halczenko, +6

Journal of Medicinal Chemistry

Molecular PharmacologyBiochemistryDonut IconMedicineAltmetric Attention Score +10

Characterization of the integrin specificities of disintegrins isolated from American pit viper venoms.

Robert M. Scarborough, Jack W. Rose, M.A. Naughton, +5

Journal of Biological Chemistry

Non-Peptide Fibrinogen Receptor Antagonists. 2. Optimization of a Tyrosine Template as a Mimic for Arg-Gly-Asp

Melissa S. Egbertson, C. T.‐C. CHANG, Mark E. Duggan, +6

Journal of Medicinal Chemistry

Interaction of fibrinogen with its platelet receptor. Differential effects of alpha and gamma chain fibrinogen peptides on the glycoprotein IIb-IIIa complex.

Joel Bennett, Sanford J. Shattil, Judith Power, +1

Journal of Biological Chemistry

Platelet receptor recognition domains on the .alpha. chain of human fibrinogen: structure-function analysis

Jacek Hawiger, Marek Kloczewiak, Maria A. Bednarek, +1

Biochemistry

Potent in Vitro and in Vivo Inhibitors of Platelet Aggregation Based Upon the Arg-Gly-Asp Sequence of Fibrinogen. (Aminobenzamidino)succinyl (ABAS) Series of Orally Active Fibrinogen Receptor Antagonists

Jeffery A. Zablocki, Joseph G. Rico, Robert B. Garland, +6

Journal of Medicinal Chemistry

PharmacotherapyPlatelet AggregationMolecular PharmacologyThrombosisMedicinal Chemistry +19

From Peptide to Non-Peptide. 2. The de Novo Design of Potent, Non-peptidal Inhibitors of Platelet Aggregation Based on a Benzodiazepinedione Scaffold

Robert S. McDowell, Brent Blackburn, Thomas R. Gadek, +6

Journal of the American Chemical Society

Altmetric Attention ScorePeptide SciencePharmacotherapyPeptide TherapeuticsChemical Biology +20

Direct design of a potent non-peptide fibrinogen receptor antagonist based on the structure and conformation of a highly constrained cyclic RGD peptide

Thomas W. Ku, Fadia E. Ali, Linda S. Barton, +6

Journal of the American Chemical Society

Peptide EngineeringAltmetric Attention ScorePeptide SciencePeptide TherapeuticsChemical Biology +20