Gene · 2001 · 373 citations · 34 references
Life SciencesGeneticsMolecular BiologyGene ExpressionMetabolic RegulationTranscriptional RegulationCholesterol BiosynthesisCholesterol MetabolismEnzyme InductionLipid HomeostasisLipid MetabolismSteroidogenic EnzymesCholesterol 7 Alpha-hydroxylase RegulationCholesterol 7 Alpha-hydroxylationLiver X ReceptorsOrphan ReceptorsSterol Regulatory Element-binding Proteins
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Identification of a Nuclear Receptor for Bile Acids
Makoto Makishima, Arthur Y. Okamoto, Joyce J. Repa et al. · Science · 1999 · 2.7K citations
Bile Acids: Natural Ligands for an Orphan Nuclear Receptor
Derek J. Parks, Steven G. Blanchard, Randy K. Bledsoe et al. · Science · 1999 · 2.2K citations
An oxysterol signalling pathway mediated by the nuclear receptor LXRα
Bethany A. Janowski, Patricia J. Willy, Thota Rama Devi et al. · Nature · 1996 · 1.7K citations
Endogenous Bile Acids Are Ligands for the Nuclear Receptor FXR/BAR
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An Orphan Nuclear Receptor Activated by Pregnanes Defines a Novel Steroid Signaling Pathway
Steven A. Kliewer, John T. Moore, Laura Wade et al. · Cell · 1998 · 1.5K citations · Full text