Endogenous Bile Acids Are Ligands for the Nuclear Receptor FXR/BAR

A Cold-Inducible Coactivator of Nuclear Receptors Linked to Adaptive Thermogenesis

Pere Puigserver, Zhidan Wu, Cheol Won Park et al. · Cell · 1998 · 3.8K citations · Full text

Life Sciences, Molecular Biology, Physiology +16

Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors α and δ

Barry M. Forman, Jasmine Chen, Ronald M. Evans · Proceedings of the National Academy of Sciences · 1997 · 2.1K citations

Life Sciences, Biochemistry, Pharmacology +17

Direct repeats as selective response elements for the thyroid hormone, retinoic acid, and vitamin D3 receptors

Kazuhiko Umesono, Kevin K. Murakami, Catherine C. Thompson et al. · Cell · 1991 · 1.7K citations · Full text

Medicine, Genetics, Molecular Genetics +15

An oxysterol signalling pathway mediated by the nuclear receptor LXRα

Bethany A. Janowski, Patricia J. Willy, Thota Rama Devi et al. · Nature · 1996 · 1.7K citations

Life Sciences, Molecular Biology, Pharmacology +11

An Orphan Nuclear Receptor Activated by Pregnanes Defines a Novel Steroid Signaling Pathway

Steven A. Kliewer, John T. Moore, Laura Wade et al. · Cell · 1998 · 1.5K citations · Full text

Life Sciences, Biochemistry, Endocrinology +16