Betas are brought into the fold

β‐Peptides: Synthesis by <i>Arndt‐Eistert</i> homologation with concomitant peptide coupling. Structure determination by NMR and CD spectroscopy and by X‐ray crystallography. Helical secondary structure of a β‐hexapeptide in solution and its stability towards pepsin

Dieter Seebàch, Mark Overhand, Florian N. M. Kühnle et al. · Helvetica Chimica Acta · 1996 · 719 citations

Life Sciences, Biochemistry, Protein Biochemistry +16

β-Peptide Foldamers:  Robust Helix Formation in a New Family of β-Amino Acid Oligomers

Daniel H. Appella, Laurie A. Christianson, Isabella L. Karle et al. · Journal of the American Chemical Society · 1996 · 686 citations

Life Sciences, Biochemistry, Biophysics +13

Synthetic molecules that fold into a pleated secondary structure in solution

R. Scott Lokey, Brent L. Iverson · Nature · 1995 · 540 citations

Life Sciences, Biochemistry, Chemistry +14

Organic synthesis. Today and tomorrow

J. F. W. McOmie · Endeavour · 1982 · 102 citations

Natural Sciences, Chemistry, Organic Chemistry +4

Triurea Derivatives of Diethylenetriamine as Potential Templates for the Formation of Artificial β-Sheets¹

James S. Nowick, Sami Mahrus, Eric M. Smith et al. · Journal of the American Chemical Society · 1996 · 89 citations

Natural Sciences, Chemistry, Medicinal Chemistry +14