Florian N. M. Kühnle

β‐Peptides: Synthesis by <i>Arndt‐Eistert</i> homologation with concomitant peptide coupling. Structure determination by NMR and CD spectroscopy and by X‐ray crystallography. Helical secondary structure of a β‐hexapeptide in solution and its stability towards pepsin

Dieter Seebàch, Mark Overhand, Florian N. M. Kühnle et al. · Helvetica Chimica Acta · 1996 · 719 citations

Life Sciences, Biochemistry, Protein Biochemistry +16

Preparation and Structural Analysis of Several New α,α,α′,α′‐Tetraaryl‐1,3‐dioxolane‐4,5‐dimethanols (TADDOL's) and TADDOL analogs, their evaluation as titanium ligands in the enantioselective addition of methyltitanium and diethylzinc reagents to benzaldehyde, and refinement of the mechanistic hypothesis

Yoshio Ito, Xavier Ariza, Albert K. Beck et al. · Helvetica Chimica Acta · 1994 · 138 citations

Natural Sciences, Chemistry, Medicinal Chemistry +13

Preparation of the PdCl₂ Complex of TADDOP, the Bis(diphenylphosphinite) of TADDOL: Use in enantioselective 1,3‐diphenylallylations of nucleophiles and discussion of the mechanism

Dieter Seebàch, Edmée Devaquet, Alexander Ernst et al. · Helvetica Chimica Acta · 1995 · 93 citations

Natural Sciences, Chemistry, Catalysis +11

A simplified synthesis of (±)-1,2-diphenyl-1,2-diaminoethane (1) from benzaldehyde and ammonia. Revision of the structures of the long-known intermediates “hydrobenzamide” and “amarine”

E. J. Corey, Florian N. M. Kühnle · Tetrahedron Letters · 1997 · 54 citations

Natural Sciences, Biochemistry, Chemistry +3

Studies on the Conformation of Boc‐Protected (<i>S</i>)‐(+)‐Isovaline Homopeptide Methyl Esters in the Solid State and in Solution

Bernhard Jaun, Masakazu Tanaka, Paul Seiler et al. · Liebigs Annalen · 1997 · 44 citations

Life Sciences, Biochemistry, Chemistry +12