Concepedia

Development of carboxylic acid replacements in indole-N-acetamide inhibitors of hepatitis C virus NS5B polymerase

Ian Stansfield, Marco Pompei, Immacolata Conte, Caterina Ercolani, Giovanni Migliaccio, Mark Jairaj, Claudio Giuliano, Michael Rowley, Frank Narjes

Bioorganic & Medicinal Chemistry Letters · 2007 · 34 citations · 13 references

DOI

Concepts

References

13

Replication of Subgenomic Hepatitis C Virus RNAs in a Hepatoma Cell Line

Volker Lohmann, Frank Körner, Jan Oliver Koch et al. · Science · 1999 · 2.8K citations

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Crystal structure of the RNA-dependent RNA polymerase of hepatitis C virus

Stéphane Bressanelli, Licia Tomei, Alain Roussel et al. · Proceedings of the National Academy of Sciences · 1999 · 568 citations

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Side effects of therapy of hepatitis C and their management

Michael Fried · Hepatology · 2002 · 556 citations · Full text

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Inhibition of Hepatitis C Virus RNA Replication by 2′-Modified Nucleoside Analogs

Steven S. Carroll, Joanne E. Tomassini, Michele Bosserman et al. · Journal of Biological Chemistry · 2003 · 338 citations · Full text

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Discovery of α,γ-Diketo Acids as Potent Selective and Reversible Inhibitors of Hepatitis C Virus NS5b RNA-Dependent RNA Polymerase

Vincenzo Summa, Alessia Petrocchi, Paola Pace et al. · Journal of Medicinal Chemistry · 2003 · 122 citations · Full text

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