Mark Jairaj

Extending the half-life of a fab fragment through generation of a humanized anti-human serum albumin Fv domain: An investigation into the correlation between affinity and serum half-life

Ralph Adams, Laura Griffin, Joanne Compson et al. · mAbs · 2016 · 67 citations · Full text

Life Sciences, Biochemistry, Biology +17

DIRECT DETERMINATION OF UNBOUND INTRINSIC DRUG CLEARANCE IN THE MICROSOMAL STABILITY ASSAY

Claudio Giuliano, Mark Jairaj, Christian Zafiu et al. · Drug Metabolism and Disposition · 2005 · 52 citations

Pharmacy, Pharmacokinetics, Pharmacology +17

A Mixture of Functionally Oligoclonal Humanized Monoclonal Antibodies That Neutralize Clostridium difficile TcdA and TcdB with High Levels of<i>In Vitro</i>Potency Shows<i>In Vivo</i>Protection in a Hamster Infection Model

Nicola L. Davies, Joanne Compson, Brendon MacKenzie et al. · Clinical and Vaccine Immunology · 2013 · 51 citations · Full text

Life Sciences, Immunology, Infectious Diseases +13

Fab-dsFv: A bispecific antibody format with extended serum half-life through albumin binding

Emma Davé, Ralph Adams, Oliver Zaccheo et al. · mAbs · 2016 · 43 citations · Full text

Pharmacy, Biochemistry, Molecular Biology +17

Development of carboxylic acid replacements in indole-N-acetamide inhibitors of hepatitis C virus NS5B polymerase

Ian Stansfield, Marco Pompei, Immacolata Conte et al. · Bioorganic & Medicinal Chemistry Letters · 2007 · 34 citations

Medicine, Medicinal Chemistry, Pharmacology +11