Immacolata Conte

2-(2-Thienyl)-5,6-dihydroxy-4-carboxypyrimidines as Inhibitors of the Hepatitis C Virus NS5B Polymerase:  Discovery, SAR, Modeling, and Mutagenesis

Uwe Koch, Barbara Attenni, Savina Malancona et al. · Journal of Medicinal Chemistry · 2006 · 86 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +17

Discovery of (7<i>R</i>)-14-Cyclohexyl-7-{[2-(dimethylamino)ethyl](methyl) amino}-7,8-dihydro-6<i>H</i>-indolo[1,2-<i>e</i>][1,5]benzoxazocine-11-carboxylic Acid (MK-3281), a Potent and Orally Bioavailable Finger-Loop Inhibitor of the Hepatitis C Virus NS5B Polymerase

Frank Narjes, Benedetta Crescenzi, Marco Ferrara et al. · Journal of Medicinal Chemistry · 2010 · 66 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Evolution, synthesis and SAR of tripeptide α-ketoacid Inhibitors of the hepatitis C virus NS3/NS4A serine protease

Stefania Colarusso, Benjamin Gerlach, Uwe Koch et al. · Bioorganic & Medicinal Chemistry Letters · 2002 · 52 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +12

Tetracyclic indole inhibitors of hepatitis C virus NS5B-polymerase

Ian Stansfield, Caterina Ercolani, Angela Mackay et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 52 citations

Medicine, Medicinal Chemistry, Pharmacology +14

Identification of thieno[3,2-b]pyrroles as allosteric inhibitors of hepatitis C virus NS5B polymerase

Jesus M. Ontoria, José Ignacio Martı́n Hernando, Savina Malancona et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 45 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +12