Stefania Colarusso

A designed P1 cysteine mimetic for covalent and non-covalent inhibitors of HCV NS3 protease

Frank Narjes, Konrad F. Koehler, Uwe Koch et al. · Bioorganic & Medicinal Chemistry Letters · 2002 · 181 citations · Full text

P1 Cysteine Mimetic, Biochemistry, Natural Sciences +8

Inhibition of the Hepatitis C Virus NS3/4A Protease

Stefania Di Marco, Menico Rizzi, Cinzia Volpari et al. · Journal of Biological Chemistry · 2000 · 125 citations · Full text

2-(2-Thienyl)-5,6-dihydroxy-4-carboxypyrimidines as Inhibitors of the Hepatitis C Virus NS5B Polymerase:  Discovery, SAR, Modeling, and Mutagenesis

Uwe Koch, Barbara Attenni, Savina Malancona et al. · Journal of Medicinal Chemistry · 2006 · 86 citations · Full text

α-Ketoacids Are Potent Slow Binding Inhibitors of the Hepatitis C Virus NS3 Protease

Frank Narjes, Mirko Brunetti, Stefania Colarusso et al. · Biochemistry · 2000 · 73 citations

Viral Replication, Protein Assembly, Hepatitis C Virus +18

Discovery of (7<i>R</i>)-14-Cyclohexyl-7-{[2-(dimethylamino)ethyl](methyl) amino}-7,8-dihydro-6<i>H</i>-indolo[1,2-<i>e</i>][1,5]benzoxazocine-11-carboxylic Acid (MK-3281), a Potent and Orally Bioavailable Finger-Loop Inhibitor of the Hepatitis C Virus NS5B Polymerase

Frank Narjes, Benedetta Crescenzi, Marco Ferrara et al. · Journal of Medicinal Chemistry · 2010 · 65 citations · Full text