Konrad F. Koehler

Modeling of the bryostatins to the phorbol ester pharmacophore on protein kinase C.

Paul A. Wender, C. M. CRIBBS, Konrad F. Koehler et al. · Proceedings of the National Academy of Sciences · 1988 · 201 citations · Full text

Drug Target, Chemical Biology, Indole Alkaloids +16

A designed P1 cysteine mimetic for covalent and non-covalent inhibitors of HCV NS3 protease

Frank Narjes, Konrad F. Koehler, Uwe Koch et al. · Bioorganic & Medicinal Chemistry Letters · 2002 · 181 citations · Full text

P1 Cysteine Mimetic, Biochemistry, Natural Sciences +8

Analysis of the phorbol ester pharmacophore on protein kinase C as a guide to the rational design of new classes of analogs.

Paul A. Wender, Konrad F. Koehler, Nancy A. Sharkey et al. · Proceedings of the National Academy of Sciences · 1986 · 155 citations · Full text

Drug Target, Chemoprevention Strategy, Alkaloid Teleocidin B +17

Thyroid Receptor Ligands. 1. Agonist Ligands Selective for the Thyroid Receptor β₁

Ye Liu, Yilin Li, Karin Mellström et al. · Journal of Medicinal Chemistry · 2003 · 140 citations · Full text

Ligands Selective, Molecular Pharmacology, Chain Length +16

Synthetic and computer-assisted analyses of the pharmacophore for the benzodiazepine receptor inverse agonist site

M.S. Allen, Mark L. Trudell, Timothy J. Hagen et al. · Journal of Medicinal Chemistry · 1990 · 122 citations