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Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury

Alexei Degterev, Zhihong Huang, Michael Boyce et al. · Nature Chemical Biology · 2005 · 3K citations

Medicine, Medicinal Chemistry, Pharmacology +17

Caspase-8 regulates TNF-α-induced epithelial necroptosis and terminal ileitis

Claudia Günther, Eva Martini, Nadine Wittkopf et al. · Nature · 2011 · 882 citations

Life Sciences, Immunology, Pathology +14

Rip1 (Receptor-interacting protein kinase 1) mediates necroptosis and contributes to renal ischemia/reperfusion injury

Andreas Linkermann, Jan Hinrich Bräsen, Nina Himmerkus et al. · Kidney International · 2012 · 459 citations

Medicine, Molecular Biology, Nephrology +15

Apoptosis-Inducing Factor Triggered by Poly(ADP-Ribose) Polymerase and Bid Mediates Neuronal Cell Death after Oxygen-Glucose Deprivation and Focal Cerebral Ischemia

Carsten Culmsee, Changlian Zhu, Stefan Landshamer et al. · Journal of Neuroscience · 2005 · 338 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Necrostatin: A Potentially Novel Cardioprotective Agent?

Christopher Smith, Sean M. Davidson, Shiang Y. Lim et al. · Cardiovascular Drugs and Therapy · 2007 · 326 citations

Medicine, Cardiology, Pharmacology +10