Concepedia

Caspase-8 regulates TNF-α-induced epithelial necroptosis and terminal ileitis

Claudia Günther, Eva Martini, Nadine Wittkopf, Kerstin Amann, Benno Weigmann, Helmut Neumann, Maximilian J. Waldner, Stephen Μ. Hedrick, Stefan Tenzer, Markus F. Neurath,

Nature · 2011 · 882 citations · 19 references

DOI

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References

19

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

Toshiro Sato, Robert G.J. Vries, Hugo J.G. Snippert et al. · Nature · 2009 · 7.2K citations

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Phosphorylation-Driven Assembly of the RIP1-RIP3 Complex Regulates Programmed Necrosis and Virus-Induced Inflammation

Young-Sik Cho, Sreerupa Challa, David Moquin et al. · Cell · 2009 · 2.4K citations · Full text

, , +15

Receptor Interacting Protein Kinase-3 Determines Cellular Necrotic Response to TNF-α

Sudan He, Lai Wang, Lin Miao et al. · Cell · 2009 · 2.2K citations

, , +10

Identification of RIP1 kinase as a specific cellular target of necrostatins

Alexei Degterev, Junichi Hitomi, Megan Germscheid et al. · Nature Chemical Biology · 2008 · 2K citations · Full text

, , +14

Fas triggers an alternative, caspase-8–independent cell death pathway using the kinase RIP as effector molecule

Nils Holler, Rossana Zaru, Olivier Micheau et al. · Nature Immunology · 2000 · 1.9K citations

, , +14