The Histone Deacetylase Inhibitor ITF2357 Decreases Surface CXCR4 and CCR5 Expression on CD4+ T-Cells and Monocytes and is Superior to Valproic Acid for Latent HIV-1 Expression in Vitro - Concepedia

Concepedia

Publication | Open Access

The Histone Deacetylase Inhibitor ITF2357 Decreases Surface CXCR4 and CCR5 Expression on CD4+ T-Cells and Monocytes and is Superior to Valproic Acid for Latent HIV-1 Expression in Vitro

DOI Full Paper Access

82

Citations

54

References

2010

Year

Shay Matalon, Brent E. Palmer, Marcel F. Nold, Antonio Furlan, Afework Kassu, Gianluca Fossati, Paolo Mascagni, Charles A. Dinarello

JAIDS Journal of Acquired Immune Deficiency Syndromes

Abstract

ITF2357 is superior to VPA in inducing HIV-1 from latently infected cells. Safely used in humans, ITF2357 is an attractive candidate for HIV-1 clinical purging.

References

	Year	Citations

Page 1