Concepedia

Ligand Binding to Wild-type and E-B13Q Mutant Insulins: A Three-state Allosteric Model System Showing Half-site Reactivity

Curtis R. Bloom, Wonjae E. Choi, Peter S. Brzović, Niels C. Kaarsholm, Michael F. Dunn

Journal of Molecular Biology · 1995 · 44 citations · 0 references

Concepts

Life SciencesBiochemistryEndocrinologyBiomolecular ModelingStructural BiologyAllosteric RegulationAllosteric Regulation ModelingLigand BindingProtein-ligand BindingReceptor ModelingReceptor-ligand InteractionsAllosteric Binding MechanismsAllosteric Ligand BindingAllosteric Protein-ligand RecognitionInsulin BiochemistryLigand Binding AffinityMulti-state Binding ModelsMultistate Binding ModelsReactivity