Publication | Closed Access
Effect of Whey Composition on Ultrafiltration Performance
22
Citations
12
References
1998
Year
Clarification PhBiomanufacturingEngineeringClarification ProcedureEnvironmental EngineeringMedicineBiochemical EngineeringWater PurificationFoulingMembrane CharacterizationMembrane BiologyMembrane FoulingFood EngineeringFood ProcessingMembrane ProcessUltrafiltration PerformanceMembrane TechnologyProtein Purification
The ultrafiltration (UF) of acid, cheese, and Shrikhand wheys is strongly affected by membrane fouling. UF membrane performance is significantly improved by a clarification procedure consisting of raising the pH to 7.5 and filtering out the precipitate. This improvement due to clarification can be attributed not only to the reduction in Ca salts but also to the reduced concentration of high molecular weight proteins such as immunoglobulin G, which have isoelectric points near the clarification pH. UF data with previously well-characterized membranes showed that the flux/protein rejection characteristics of the clarified wheys are similar to those for filtration of single-component (BSA) solutions. Keywords: Clarification; pretreatment; whey; ultrafiltration; immunoglobulins
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