X-ray crystal structure of JNK2 complexed with the p38α inhibitor BIRB796: Insights into the rational design of DFG-out binding MAP kinase inhibitors

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Airlie J. McCoy, Ralf W. Grosse‐Kunstleve, Laurent C. Storoni et al. · Acta Crystallographica Section D Biological Crystallography · 2005 · 1.6K citations · Full text

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Inhibition of p38 MAP kinase by utilizing a novel allosteric binding site

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BIRB796 Inhibits All p38 MAPK Isoforms in Vitro and in Vivo

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