Purification, characterization and selective inhibition of human prostaglandin G/H synthase 1 and 2 expressed in the baculovirus system

Jim Barnett, Joan M. Chow, D.H. Ives, +10

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology

Selective InhibitionMolecular VirologyBiochemistryBaculovirus SystemNatural Sciences +6

Design of Annulated Pyrazoles as Inhibitors of HIV-1 Reverse Transcriptase

Zachary K. Sweeney, Seth F. Harris, Nidhi Arora, +24

Journal of Medicinal Chemistry

Reverse Transcriptase EnzymeMolecular BiologyCell CultureNew SeriesAntiviral Drug +15

Cutting Edge: IL-1 Receptor-Associated Kinase 4 Structures Reveal Novel Features and Multiple Conformations

A. Kuglstatter, Armando G. Villaseñor, David E. Shaw, +6

The Journal of Immunology

Expression of human dopamine β-hydroxylase in Drosophila Schneider 2 cells

Bin Li, Stan Tsing, Alan Kosaka, +5

Biochemical Journal

The Crystal Structure of JNK2 Reveals Conformational Flexibility in the MAP Kinase Insert and Indicates Its Involvement in the Regulation of Catalytic Activity

David E. Shaw, Sandra M. Wang, Armando G. Villaseñor, +5

Journal of Molecular Biology

Crystal StructureProtein FunctionSignal TransductionSignaling PathwayBiochemistry +9

Insights into the conformational flexibility of Bruton's tyrosine kinase from multiple ligand complex structures

A. Kuglstatter, April Wong, Stan Tsing, +7

Protein Science

Protein AssemblyTyrosine KinaseMolecular BiologyChemical BiologyBtk Kinase Domain +18

Activation Mechanism and Steady State Kinetics of Bruton's Tyrosine Kinase

Marie Dinh, D. Grünberger, Hoangdung Ho, +7

Journal of Biological Chemistry

X-ray crystal structure of JNK2 complexed with the p38α inhibitor BIRB796: Insights into the rational design of DFG-out binding MAP kinase inhibitors

A. Kuglstatter, M. Ghate, Stan Tsing, +4

Bioorganic & Medicinal Chemistry Letters

P38α Inhibitor Birb796BiochemistryMedicineNatural SciencesProtein X-ray Crystallography +7

Monoclonal Antibodies Against <i>Trichomonas vaginalis</i>

Tong Chang, Stan Tsing, Sinfu Tzeng

Hybridoma

Production, Purification, and Characterization of Human Matrilysin (PUMP) from Recombinant Chinese Hamster Ovary Cells

Jim Barnett, Kenneth Straub, Bao Trâm Nguyen, +7

Protein Expression and Purification

OocyteDevelopmental BiologyOogenesisMedicineCell Culture +10