9-Hydroxymethylcyclopropylidenemethylenyladenine: The design, facile synthesis, isomer separation and anti-HIV-1 activities

Prevention of SIV Infection in Macaques by ( <i>R</i> )-9-(2-Phosphonylmethoxypropyl)adenine

Che‐Chung Tsai, Kathryn E. Follis, Alexander Sabó et al. · Science · 1995 · 563 citations

Medicine, Infectious Diseases, Pharmacology +17

Synthesis of carbocyclic nucleosides

Luigi A. Agrofoglio, Edouard Suhas, Audrey Farèse et al. · Tetrahedron · 1994 · 379 citations

Pharmacy, Chemistry, Medicinal Chemistry +12

Both 2′,3′-dideoxythymidine and its 2′,3′-unsaturated derivative (2′,3′-dideoxythymidinene) are potent and selective inhibitors of human immunodeficiency virus replication in vitro

Masanori Baba, Rudi Pauwels, Piet Herdewijn et al. · Biochemical and Biophysical Research Communications · 1987 · 344 citations

Life Sciences, Medicinal Chemistry, Molecular Biology +13

3'-Substituted 2',3'-dideoxynucleoside analogs as potential anti-HIV (HTLV-III/LAV) agents

Piet Herdewijn, Jan Balzarini, Erik De Clercq et al. · Journal of Medicinal Chemistry · 1987 · 296 citations

Medicine, Medicinal Chemistry, Pharmacology +15

Activities of the four optical isomers of 2',3'-dideoxy-3'-thiacytidine (BCH-189) against human immunodeficiency virus type 1 in human lymphocytes

Raymond F. Schinazi, C. K. CHU, A Peck et al. · Antimicrobial Agents and Chemotherapy · 1992 · 265 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +9